The structural resolution of PTEX, the translocon of virulence proteins and malaria parasites. [ 2014 - 2016 ]

Research Grant

Researchers: Prof Brendan Crabb (Principal investigator) ,  Dr Paul Gilson ,  Dr Travis Beddoe ,  Prof Tania De Koning-Ward

Brief description The extraordinary virulence of malaria parasites is in part due to their ability to export hundreds of proteins into their red blood cell hosts that help them obtain nutrients and avoid the immune system. Recently we discovered the molecular machine that exports proteins into the host cell and we now wish to establish how it works so drugs can be tailored to block the machine and kill the parasites.

Funding Amount $AUD 561,028.33

Funding Scheme Project Grants

Notes Standard Project Grant