grant

Structural and functional studies of T-cell mediated recognition of microbial lipids presented by CD1c [ 2014 - 2017 ]

Also known as: T cell recognition of CD1c presenting microbial lipids

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1073485]

Researchers: Dr Kwok Wun (Principal investigator)

Brief description The CD1c molecule plays an important role in the immune system by presenting lipid-based antigen of pathogens to the surface of an antigen presenting cell (APC) that is infected by the pathogen. Once a T cell receptor (TCR), which is expressed on the surface of a Killer T cell, recognises CD1c presenting pathogenic lipid, any infected cells will be destroyed. My research will look at the molecular mechanism of T cell recognising tuberculosis related lipids that is presented by CD1c.

Funding Amount $AUD 316,449.66

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF

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Identifiers
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ACN 633 798 857