Structural events in insulin and IGF signalling - a nanodisc approach to a problem in cancer, diabetes and Alzheimer's disease [ 2016 - ]

Research Grant

Researchers: A/Pr Michael Lawrence (Principal investigator) ,  A/Pr Hans Elmlund

Brief description Insulin and its insulin-like growth factors play a major role in three major disease states facing ageing Australians—diabetes, cancer and Alzheimer's disease. We aim to understand how these proteins send messages into cells via their so-called receptors. We will isolate the receptor molecules from cells and then image them in an advanced electron microscope to produce three-dimensional images. Our findings will have implications for the design of therapeutics targeting the above three diseases.

Funding Amount $752,403.00

Funding Scheme Project Grants

Notes Standard Project Grant