Structural and drug discovery studies of medically important protein complexes [ 2008 - 2011 ]

Research Grant

Researchers: Dr Galina Polekhina (Principal investigator)

Brief description My research is focused on structural studies of medically important biological systems, where specific protein complex formation contributes to human illnesses. I use X-ray crystallography to visualize the whole complex at atomic resolution as well as to determine whether binding partners have undergone changes in shape upon complex formation. This structural information then helps me in drug design with goals to either disrupt or modulate the complex.

Funding Amount $AUD 438,577.14

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF