grant

Structural basis for inhibition of malaria invasion by targeting the apical membrane antigen of Plasmodium falciparum. [ 2008 - 2010 ]

Also known as: Inhibition of malaria by targeting functional areas on AMA1.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/487339]

Researchers: A/Pr Michael Foley (Principal investigator) ,  Dr Andrew Coley

Brief description 3 million children die every year from malaria infections. A leading vaccine candidate is a protein from the malaria parasite called AMA1. Humans that have been infected with malaria make antibodies to this protein which can kill parasites, however little is known about how this occurs. We aim to identify regions of the protein that generate antibodies that prevent malaria parasites from invading human cells and help in the search for a vaccine against malaria.

Funding Amount $AUD 434,134.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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