grant

The structural basis for glutamate transporter function [ 2013 - 2015 ]

Also known as: Glutamate transporters: the vacuum cleaners of the brain

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1048784]

Researchers: A/Pr Renae Ryan (Principal investigator) ,  Prof Robert Vandenberg

Brief description Glutamate transporters are vacuum cleaners in the brain that suck the neurotransmitter glutamate into cells. When the glutamate vacuum breaks down or becomes blocked, glutamate levels outside cells increase, leading to cell death in the brain. This process underlies the damage in many brain diseases including Alzheimer’s disease and stroke. The aim of this project is to understand the mechanism of the glutamate vacuum cleaner so we can develop therapeutics to fix it when it breaks down.

Funding Amount $AUD 373,144.09

Funding Scheme Project Grants

Notes Standard Project Grant

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