Strategies for healthy osteocytes [ 2009 - 2012 ]

Research Grant

Researchers: Prof Gerald Atkins (Principal investigator) ,  A/Pr Paul Anderson ,  Prof David Findlay ,  Prof Lynda Bonewald

Brief description Osteocytes (OY) are the most abundant cell type in bone whose high density and viability are essential for healthy bone. We have found that vitamin K, vitamin D and strontium, promote human OY differentiation. We will test these in novel models of human OY differentiation and survival, and in animal models of bone loss associated with vitamin D deficiency, menopause and glucocorticoid treatment. Our work will lead to a better understanding of human OY and give a new approach to treat osteoporosis.

Funding Amount $AUD 511,294.64

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant