grant

Stimulation of human immunodeficiency virus type 1 (HIV-1) specific cytolytic effector function using allogeneic cell immunotherapy [ 2012 - 2015 ]


Funded by National Health and Medical Research Council
Managed by The University of Western Australia
Managed by University of Western Australia
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1034858]

Researchers: A/Pr Lloyd D'Orsogna (Principal investigator) ,  A/Pr Campbell Witt

Brief description A preventative HIV vaccine is not currently available. Stimulation of the bodies own immune cells (T-cells) may be associated with better protection against the virus, and we have recently discovered that T-cells already present in humans are frequently stimulated by foreign (allogeneic) cells. Therefore we aim to determine if “vaccination” with allogeneic cells could stimulate a HIV specific immune response in humans. These results could have important implications for HIV vaccine design.

Funding Amount $AUD 377,648.35

Funding Scheme Project Grants

Notes New Investigator Grant

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Applied Immunology (Incl. Antibody Engineering, Xenotransplantation and T-Cell Therapies) | Immunology | Medical and Health Sciences | T cell immunotherapy | T cell memory | T cell receptor | human immunodeficiency virus (HIV) | human leukocyte antigen (HLA) | vaccine | vaccine development | viral immunity |
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