Steroidogenic factor-1, a novel regulator of hepatic stellate cell function [ 2010 - 2012 ]

Also known as: SF-1 in hepatic stellate cells

Research Grant

[Cite as]

Researchers: Prof Christopher Liddle (Principal investigator) ,  Dr Michael Downes

Brief description Recently, we have discovered that steroidogenic factor-1, a specialized protein that directs cells to make steroid hormones, is present in cells in the liver called stellate cells. This may play a vital role in how the liver responds to damage and whether the liver will the scar and move on to cirrhosis. Our experiments will determine if this is so and how this system functions. This work will provide a basis for future treatments to improve or prevent cirrhosis in liver disease patients.

Funding Amount $AUD 589,458.22

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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