grant

Statistical methods for identifying structural variation in tumour genomes using Next Generation sequencing [ 2010 - 2012 ]

Also known as: Methods for identifying mutations in tumour genomes

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/637357]

Researchers: Prof Anthony Papenfuss (Principal investigator) ,  Dr Matthew Wakefield

Brief description New DNA sequencing technology can sequence a tumour genome affordably in 2 weeks. This re-sequencing data can be used to find small mutations and large-scale chromosomal rearrangements that together are the drivers of cancer. These may one day be used to guide cancer therapy. This project will develop new algorithms for finding mutations and apply these to discover the genetic basis of drug resistance in a model lymphoma system.

Funding Amount $AUD 243,458.41

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Subjects
Biochemistry and Cell Biology | Biological Sciences | Bioinformatics | Next Generation sequencing | bioinformatics | cancer | mutation | mutation detection | structural genome variation | understanding genome structure and evolution |
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