STABILISING G PROTEIN-COUPLED RECEPTORS FOR DRUG DISCOVERY [ 2015 - 2017 ]

Research Grant

Researchers: Dr Daniel Scott (Principal investigator)

Brief description Prescription drugs targeting human proteins called GPCRs are sold as effective treatments for many diseases. However, there are over 800 different types of GPCRs in the human body and only a small fraction is targeted by drugs, mainly because GPCRs are unstable and thus difficult to work with in the laboratory. We are applying newly developed technologies to engineer stabilised ?1-adrenoceptors, a class of GPCRs, for drug discovery against cardiovascular diseases, epilepsy and neurodegeneration

Funding Amount $AUD 628,140.00

Funding Scheme Project Grants

Notes New Investigator Grant