grant

Specific roles of the transmembrane exoloops and the LDLa module in the activity of relaxin and INSL3 receptors [ 2010 - 2012 ]

Also known as: Functional analysis of relaxin and INSL3 receptors

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/628427]

Researchers: Prof Ross Bathgate (Principal investigator) ,  A/Pr Paul Gooley

Brief description The peptide hormone relaxin is currently in clinical trials to treat acute heart failure. The related hormone INSL3 has important roles in fertility. We will continue our previously successful approaches to study the interaction of relaxin and INSL3 with their cell surface receptors and the mechanisms by which the receptors function. The knowledge gained will aid in the design of smaller, more potent and orally active forms of relaxin and INSL3 for future clinical applications.

Funding Amount $AUD 598,863.53

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
Viewed: [[ro.stat.viewed]]
ACN 633 798 857