grant

Sonic hedgehog signalling in Barrett s oesophagus [ 2010 - 2012 ]

Also known as: Understanding the development of Barretts oesophagus

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/628635]

Researchers: Prof Wayne Phillips (Principal investigator) ,  Dr Nicholas Clemons Prof David Watkins

Brief description Barrett's oesophagus (BO) is a condition that arises in some patients with chronic reflux (heartburn) and increases the risk of developing cancer of the oesophagus. However, the exact mechanisms involved in its development are unknown. This project aims to investigate how a protein called sonic hedgehog might be involved using novel cell culturing techniques that allow us to model the growth of oesophageal tissue in the laboratory. This could lead to development of new therapies for treating BO.

Funding Amount $AUD 570,876.85

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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