grant

Somatic retrotransposition drives neoplastic mutagenesis in glioblastoma multiforme [ 2013 - 2015 ]

Also known as: Mobile DNA as a contributor to human brain cancer

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1042449]

Researchers: Prof Geoffrey Faulkner (Principal investigator) ,  Dr Ryan Taft

Brief description Retrotransposons are mobile genes that copy-and-paste themselves in our genome. Previously thought to represent “junk DNA”, retrotransposons are increasingly found to play major roles in biology. In a recent landmark publication in Nature, we demonstrated that retrotransposons move in the healthy human brain. In the current study, we will use cutting-edge technologies to determine whether brain cancer can occur as a result. This will provide new perspectives of the genetic basis for cancer.

Funding Amount $AUD 667,342.65

Funding Scheme Project Grants

Notes Standard Project Grant

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