Solving delivery of gene therapy for control of Human Immunodeficiency Virus infection [ 2017 - 2019 ]

Research Grant

Researchers: Prof Anthony Kelleher (Principal investigator) ,  A/Pr Stuart Turville ,  Dr Cody Allison ,  Dr Kazuo Suzuki ,  Prof Geoffrey Symonds

Brief description Antiretroviral therapy free control of Human Immunodeficiency Virus (HIV) infection requires control of the viral reservoir. We have a unique approach, aimed at enforcing HIV latency by targeting highly conserved regions in the viral promoter. These constructs completely silence viral transcription for long periods of time. We intend to develop & assess vectors that are specifically targeted to the reservoir and which can enforce viral latency despite immune activation or viral variation.

Funding Amount $AUD 783,256.91

Funding Scheme Project Grants

Notes Standard Project Grant