Small Molecule Modulators of Complement in Metabolism and Obesity [ 2012 - 2015 ]

Research Grant

Researchers: Prof David Fairlie (Principal investigator) ,  Prof Katherine Cianflone ,  Prof Lindsay Brown

Brief description We have discovered that certain inflammatory proteins in the blood that are produced in the immune response to infection are involved in regulating the storage and burn off of fat in adipose tissue in the abdomen. These proteins bind to the surfaces of both fat and immune cells. We will study the effects of new drugs that compete with these blood proteins for the surfaces of these cells, since our experiments indicate that such drugs can potentially prevent and reverse fat deposition in rats fed a high-fat, high-carbohydrate, diet.

Funding Amount $AUD 682,820.65

Funding Scheme Project Grants

Notes Standard Project Grant