grant

Small molecule Inhibitors of glutathione transferase omega 1-1 (GSTO1-1) for the treatment of inflammatory disease [ 2019 - ]

Also known as: 5011440

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1156455]

Brief description In this project we will develop inhibitors of GSTO1-1, an enzyme that is thought to play an important and exacerbating role in acute and life-threatening inflammatory responses such as those involved in sepsis. We will test our novel and improved compounds in vitro, determine pharmacokinetic properties, profile their selectivity, and test them for in vivo efficacy as potential anti-inflammatory candidates for the future treatment of sepsis..

Funding Amount $737,521.00

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857