Slowing progression of Alzheimer’s disease by modulating the kynurenine pathway [ 2017 - ]

Research Grant

Researchers: Prof Gilles Guillemin (Principal investigator) ,  Dr Arne Ittner ,  Dr David Lovejoy ,  Dr James Doecke ,  Dr Nady Braidy

Brief description Chronic inflammation in the brain in known to be a factor in the progression of Alzheimer's disease. We are exploring if blocking a particular enzyme in a biochemical pathway involved in inflammation, can improve symptoms, or slow progression, of the disease in animal models of AD. If results are as expected, our proposal has the potential to generate a new a therapy for AD.

Funding Amount $578,460.00

Funding Scheme Project Grants

Notes Standard Project Grant