Sirtuins and the molecular epidemiology of frailty in older men [ 2008 - 2009 ]

Research Grant

Researchers: Prof Robert Cumming (Principal investigator) ,  A/Pr Marina Kennerson ,  A/Pr Vasi Naganathan ,  Dr Rafael De Cabo ,  Prof David Le Couteur
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Brief description People in Australia are living longer and longer and yet little is known about the underlying biology of the ageing process. This project will investigate the role of a number of molecular and cellular factors in the aetiology of frailty in a group of more than 1400 older men who are already participating in the Concord Health and Ageing in Men Project. A particular focus of the project are sirtiuns, a group of enzymes recently found to be associated with longer life in several animal models.

Funding Amount $AUD 483,246.45

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant