Single versus combination pneumococcal conjugate vaccines (13PCV and PHiD-CV) for high-risk Aboriginal children (COMBO) [ 2010 - 2014 ]

Research Grant

Researchers: Prof Amanda Leach (Principal investigator) ,  A/Pr Heidi Smith-Vaughan ,  A/Pr Susan Skull ,  Ms Anne Balloch ,  Prof Edward Mulholland
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Brief description Two new pneumococcal vaccines, each offering protection from different pneumococcal strains and pathogens will soon be available. At this time, health experts do not know which vaccine will be best for Indigenous children. The hypothesis of this project is that both vaccines, given as a 4 dose schedule may be a better than 3-dose single vaccines for Indigenous and high-risk children. The vaccines' effects on immune response and on nasal colonisation with bacterial pathogens will be compared.

Funding Amount $AUD 3,017,464.55

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant