grant

A single-stranded DNA binding protein implicated in the cellular response to DNA damage. [ 2010 - 2013 ]

Also known as: A novel protein implicated in the cellular response to DNA damage.

Funded by National Health and Medical Research Council
Managed by University of Western Sydney
Managed by Western Sydney University
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/632610]

Researchers: Dr Liza Cubeddu (Principal investigator)

Brief description Humans have evolved multiple mechanisms to ensure the integrity of their genetic information, which is carried by DNA. Each cell suffers more than 100 000 insults a day to its DNA; therefore an effective DNA damage response is crucial for the maintenance of genetic integrity and for survival. This research proposal aims to explore the molecular actions of hSSB2, a newly discovered player in the cell's arsenal for repairing harmful DNA damage.

Funding Amount $AUD 503,816.01

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Chemical Sciences | Characterisation of Biological Macromolecules | DNA damage | DNA repair | Medicinal and Biomolecular Chemistry | cancer | genetic predisposition to disease | molecular mechanisms | protein structure | protein-protein interaction | ultraviolet radiation exposure |
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