A signalling endosomal network in T cell activation [ 2016 - ]

Research Grant

Researchers: Dr Jeremie Rossy (Principal investigator) ,  Dr Nicholas Ariotti (Principal investigator)

Brief description T lymphocytes play a central role in the adaptive immune response, which specifically targets pathogens and cancer cells and creates the immunological memory. Activation of sometimes as little as one single receptor on a T cell triggers a cellular signal that rapidly expands and branches out in a multitude of sub-signals. Here we will use a combination of novel microscopy approaches to visualise how a network of dedicated intracellular compartments is in charge of these processes.

Funding Amount $428,016.00

Funding Scheme Project Grants

Notes Standard Project Grant