Signaling pathways to enhance potency of AMPK-targeting drugs [ 2016 - ]

Research Grant

Researchers: A/Pr Jon Oakhill (Principal investigator) ,  Dr John Scott ,  Prof Bruce Kemp

Brief description Sedentary lifestyles and consumption of high energy foods has led to epidemics of obesity-related metabolic diseases that place enormous financial and medical burden on the Australian economy. An attractive drug target to treat these diseases is AMP-activated protein kinase (AMPK) which functions as both a cellular fuel gauge and co-ordinator of whole-body metabolism. Our goal is to improve AMPK drug potency by identifying novel processes that sensitize AMPK to drugs.

Funding Amount $661,966.00

Funding Scheme Project Grants

Notes Standard Project Grant