grant

Secretion of alpha-synuclein: A diagnostic marker for Parkinsons Disease and a clue to its (patho)physiology [ 2008 - 2010 ]

Also known as: A diagnostic test for Parkinsons Disease

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/508961]

Researchers: Prof Malcolm Horne (Principal investigator) ,  E/Pr Phillip Nagley

Brief description We have found that a protein, alpha-synuclein is low in people with Parkinson's Disease. We wish to see if this can be used as a diagnostic test for the condition. Alpha-Synuclein is thought to be important in causing Parkinson's Disease. We suspect that by finding out why less of this protein enters the blood stream in Parkinson's Disease, we may discover clues as to how alpha-synuclein causes problems in this condition.

Funding Amount $AUD 634,051.17

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Medical Infection Agents (Incl. Prions) | Medical Microbiology | Parkinson's disease | alpha-synuclein | movement disorders | neurological disease diagnosis e.g. Parkinson's | neuronal degeneration | substantia nigra | synaptic plasticity |
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