Scabies mite complement inhibitors as targets for novel therapeutics [ 2013 - 2018 ]

Research Grant

Researchers: Dr Simone Reynolds (Principal investigator)

Brief description Scabies and associated bacteria disease (pyoderma) are a significant health burden, with pyoderma implicated in rheumatic fever and heart disease. Investigations of the mechanism underlying scabies and bacteria disease links, identified scabies proteins inhibiting the human complement system. The inhibition prevents mite damage and promotes growth of bacteria. This proposal aims to elucidate the interaction between scabies, bacteria and the human host, in order to design new therapeutics.

Funding Amount $AUD 350,149.74

Funding Scheme Early Career Fellowships

Notes Australian Training ECF for Aboriginal and Torres Strait Islander Health Research