grant

Roles of Cascades of Transforming Growth Factor-beta and Matrix Metalloproteinases in the Impact of Cancer Stem Cells on the Neoplasm Formation of Oral Squamous Cell Carcinoma. [ 2012 - 2015 ]

Also known as: Impact of Cancer Stem Cells on the Neoplasm Formation of Oral Cancer.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1039888]

Researchers: Dr Beata Urban-Klein (Principal investigator)

Brief description Failure of treatment of oral cancer patients is because the specific cancer cells escape from chemo-radiotherapy. These cells feature self-renew and fast growth, which are called cancer stem cells (CSC). We will test our hypothesis “the genes of TGF-?1 and MMP initiate CSCs” using our cell-mouse models to arrest cancer progression, and verify the impact of CSC on cancer formation. This study is critical to know how to arrest CSC and offer an opportunity to develop a targeted anti-cancer therapy.

Funding Amount $AUD 81,793.82

Funding Scheme Postgraduate Scholarships

Notes Dora Lush Biomedical Postgraduate Scholarship

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Identifiers
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ACN 633 798 857