The role of the zinc finger transcriptional repressor Znf238 during nerve cell maturation [ 2011 - 2014 ]

Also known as: A rheostat for the control of gene expression during nerve cell maturation

Research Grant

[Cite as]

Researchers: A/Pr Julian Heng (Principal investigator)

Brief description Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.

Funding Amount $AUD 394,264.58

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF

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