Role of ZEB/NuRD interactions in Haematopoiesis and Lymphoid Malignancies [ 2016 - ]

Research Grant

Researchers: A/Pr Jody Haigh (Principal investigator) ,  A/Pr Ross Dickins ,  Prof Cristina Mecucci

Brief description Cancers of the blood arise from (epi)genetic changes that enable blood cells to bypass normal survival and growth checkpoints, leading to accumulation of additional mutations that drive full-scale transformation. This grant aims to understand the role of specific transcription factors (that control disease causing genes to be expressed) and how we can use a novel class of epigenetic drugs together with inhibition of these factors to selectively get rid of cancer causing blood cells in the body.

Funding Amount $810,497.00

Funding Scheme Project Grants

Notes Standard Project Grant