The role of voltage-gated Na+ and Ca2+ channels in post-inflammatory hyperexcitability of enteric neurons [ 2009 - 2012 ]

Research Grant

Researchers: A/Pr Kulmira Nurgali (Principal investigator) ,  Prof John Furness

Brief description Gastrointestinal inflammation causes changes in neurons that control gut functions (motility and secretion). These changes in neuronal properties lead to the development of post-inflammatory motility disorders. This will be the first detailed study of neuronal ion channels that are changed after inflammation in the gut. Our study will open the way to the development of therapeutic agents to treat post-inflammatory IBS and other conditions that involve disorders of motility.

Funding Amount $AUD 520,000.34

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant