grant

The role of the transcription factor IRF4 in peripheral Cd8 T cell differentiation [ 2012 - 2014 ]

Also known as: IRF4 in peripheral CD8 T cell differentiation

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1032850]

Researchers: Prof Axel Kallies (Principal investigator)

Brief description T cells protect against viral infections and fight cancer cells. In order to fulfill these roles T cells have to undergo significant phenotypic and functional changes. Our preliminary data indicate a central role for the regulator protein IRF4 in this process, as T cells that lack this protein are unable to grow and acquire the cellular tools necessary to provide protection. We wish to characterize the role of IRF4 in T cells in detail and aim to identify the processes regulated by IRF4.

Funding Amount $AUD 399,176.33

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857