grant

Role of STAT5 in defining lifespan in mouse models [ 2012 - 2015 ]

Also known as: Use of transgenic mouse models to elucidate the molecular basis of lifespan

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1025094]

Researchers: Prof Michael Waters (Principal investigator)

Brief description We seek to elucidate the molecular basis for the extended lifespan seen in the Methuselah mouse, the longest lived mouse model of ageing. This mouse lacks the receptor for growth hormone, and we have identified a major gene-regulating protein activated by the growth hormone receptor as correlating with lifespan. This project seeks to establish if this protein does indeed regulate lifespan, and to determine how it does this, particularly in relation to metabolism of toxins and free radicals.

Funding Amount $AUD 547,216.03

Funding Scheme Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]
ACN 633 798 857