The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer [ 2017 - ]

Research Grant

Researchers: A/Pr Jason Wong (Principal investigator) ,  Prof John Pimanda (Principal investigator) ,  Prof Ruud Delwel

Brief description The three dimensional organisation of genomic DNA has been recognised to play a crucial role in maintaining the stability and function of human cells. In cancer this organisation is often perturbed as a result of mutations to proteins that govern this process. This project will examine how mutations in the DNA may potentially alter the three dimensional organisation of cancer genomes and will identify links between these mutations with cancer development and patient prognosis.

Funding Amount $371,114.00

Funding Scheme Project Grants

Notes Standard Project Grant