Role of Set7 in diabetes related end-organ injury [ 2012 - 2015 ]

Research Grant

Researchers: Prof Mark Cooper (Principal investigator) ,  Prof Assam El-Osta ,  Prof Karin Jandeleit-Dahm

Brief description Diabetic complications are the major cause of the medical burden of both type 1 and type 2 diabetes. It appears that prior episodes of poor sugar control have a sustained impact by continuing to damage blood vessels and the kidney, this phenomenon is known as metabolic memory. In this study an enzyme called Set 7 which modifies the proteins wrapping DNA is considered to play a central role in this phenomenon and could be a potential target for developing new treatments to reduce the burden of diabetic complications.

Funding Amount $AUD 903,870.21

Funding Scheme Project Grants

Notes Standard Project Grant