grant

Role of PTEN catalytic function in suppression of cancer and metastasis [ 2016 - 2019 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1100307]

Brief description PTEN mutations are frequently described in various types of cancer. This proposal outlines different experimental strategies to probe how modulation of distinct PTEN functions can affect signalling pathways and be responsible for oncogenic outcomes. We will use animal models and cell lines in culture to identify new signatures/biomarkers to stratifying patients on genetic and molecular bases, and to facilitate the design of tailored combinational therapies directed toward cancer eradication.

Funding Amount $AUD 783,509.36

Funding Scheme Project Grants

Notes New Investigator Grant

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Identifiers
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ACN 633 798 857