grant

Role of primary cilia and PCP proteins in lens development: implications for lens regeneration after cataract surgery [ 2011 - 2013 ]

Also known as: Cilia and PCP in lens regeneration

Funded by National Health and Medical Research Council
Managed by The University of Sydney
Managed by University of Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1003356]

Researchers: Prof Johnston Mcavoy (Principal investigator) ,  Prof Frank Lovicu

Brief description Cataract extraction is the most common surgical procedure conducted in our hospitals today. Unfortunately, a complication of surgery is the development of a secondary cataract. This is caused by residual lens epithelial cells undergoing a wound healing response that leads to severe scarring and loss of vision. This project will identify the factors that are needed to maintain lens epithelial cells in a normal state so that they can act as stem cells that can be induced to regenerate a new lens that can transmit and focus light as normal.

Funding Amount $AUD 413,742.42

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biochemistry and Cell Biology | Biological Sciences | Cell Development, Proliferation and Death | age-related | cataracts of the lens | cell development | cell polarity | cytoskeleton | eye disease | signalling pathways | tissue regeneration | vision loss |
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