grant

The role of PLZF in regulating the antiviral activity of interferons [ 2010 - 2013 ]

Also known as: The role of PLZF in regulating interferon action

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/606425]

Researchers: Prof Bryan Williams (Principal investigator) ,  Dr Dakang Xu

Brief description Interferons are the first line of defence against viral infection. We have shown that the transcription factor promyelocytic leukemia zinc finger protein (PLZF) is a novel regulator of the interferon response. Thus we hypothesize that PLZF is a critical component of the host's innate immune system. This study will provide new insights into the understanding of signal transduction mechanisms, as well as improve our ability to modulate sensitivity to interferon to protect against viral diseases.

Funding Amount $AUD 652,005.20

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]