grant

The role of platelet derived growth factor receptor alpha (Pdgfra) in coronary vascular progenitor cells [ 2009 - 2012 ]

Also known as: The embryonic origins of the coronary circulation

Funded by National Health and Medical Research Council
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/573707]

Researchers: Dr Owen Prall (Principal investigator) ,  Dr Christine Biben

Brief description The coronary vessels supply blood to heart muscle. Blockage of coronary vessels causes heart attacks which are the leading cause of death in the Western world. A recent focus for heart attack researchers is to re-establish the blood supply to the injured area by creating new blood vessels. We have found a new gene involved in creating coronary blood vessels. We will characterize how this gene is involved in this process. Knowledge about this gene may foster new treatments for heart attack.

Funding Amount $AUD 666,840.04

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Nutrition and Dietetics | Public Health Nutrition | conditional gene knockout | developmental genes | embryonic development | ischaemic cardiomyopathy | ischaemic heart disease | myocardial infarction | platelet-derived growth factor alpha | vascular biology | vascular pathologies | vascular remodeling |
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