Role of a novel Tks5-Nck signaling pathway in cancer invasion [ 2008 - 2011 ]

Research Grant

Researchers: Dr Peter Lock (Principal investigator) ,  Prof Andrew Kaye ,  Prof Sara Courtneidge

Brief description Invasion and metastasis are major causes of death in cancer patients. Our research has uncovered a pathway that increases the invasive potential of tumour cells in vitro. We now aim to determine if the pathway is relevant in invasion and metastasis in clinically relevant models; how a drug targeting the pathway affects invasion and; the extent to which the pathway is active in human tumours. These studies may identify a new molecular target for anti-invasive drugs.

Funding Amount $AUD 560,434.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant