grant

Role of non-classical actions of androgens in musculoskeletal physiology [ 2008 - 2010 ]

Also known as: Non-classical androgen actions

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/509328]

Researchers: Dr Helen Maclean (Principal investigator) ,  A/Pr Rachel Davey

Brief description Androgens (male sex hormones) are important for growth-maintenance of muscle and bone. The classical action of androgens is to bind the androgen receptor (AR) and regulate target genes. They can also act via non-classical AR mechanisms through other cellular pathways. To understand the role of non-classical actions in the musculoskeletal system we will study mice in which androgens can only act via this pathway. This knowledge is important for the treatment of osteoporosis and muscle wasting.

Funding Amount $AUD 703,664.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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