grant

Role of NK cell-dendritic cell interactions in the induction of T cell responses involved in malarial pathogenesis [ 2009 - 2011 ]

Also known as: NK cell-DC cross-talk in malaria

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/575538]

Researchers: Dr Diana Hansen (Principal investigator)

Brief description Cerebral malaria is a devastating neurological syndrome. Recent data indicate that NK cells are involved in disease induction. NK cell function is controlled by receptors encoded by a genetic region named the Natural Killer Complex (NKC). We showed that the differential expression of NKC genes controls the degree of susceptibility to cerebral malaria. Here we will identify and characterise NKC receptors involved in pathogenesis and the mechanism by which these molecules mediate disease.

Funding Amount $AUD 338,154.38

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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