The role of NF-?B transcription factor RelA in regulatory T cell homeostasis and function [ 2014 - 2016 ]

Research Grant

Researchers: Prof Axel Kallies (Principal investigator) ,  Dr Ashish Banerjee ,  Dr George Grigoriadis

Brief description Treg cells constitute an immune regulatory cell population that is essential for the prevention of fatal autoimmunity; however, they also limit immunity against cancer. We have discovered that the factor RelA is of critical importance for Treg development and function. We now aim to illuminate the functions of RelA in detail. Understanding the molecules that impact on Treg cell biology is critical to harness their potential for clinical intervention such as treatment of autoimmunity and cancer.

Funding Amount $AUD 637,114.33

Funding Scheme Project Grants

Notes Standard Project Grant