The role of a new druggable protein and its interacting partners in blood development and blood diseases [ 2014 - ]

Research Grant

Researchers: Prof Graham Lieschke (Principal investigator) ,  Dr M. Cristina Keightley

Brief description Zbtb11 is a druggable protein that is mis-expressed in blood cancers - second biggest cause of cancer death in Australia - and liver cancer, third leading cause of death from cancer worldwide. We have found that it interacts with 2 other proteins with potential roles in these diseases. Our studies examine the nature of these Zbtb11-partner interactions and their particular consequences for blood disorders. Zbtb11 contributions to disease development will be a target for novel disease therapy.

Funding Amount $567,562.00

Funding Scheme Project Grants

Notes Standard Project Grant