The role of a new class of chromatin organising hub [ 2017 - ]

Research Grant

Researchers: Prof John Rasko (Principal investigator) ,  Prof Ryan Lister

Brief description Within the cell nucleus, specific proteins weave DNA into structured loops that are vital for normal cell function. By studying the molecules involved, we have uncovered a ‘dock’ that controls this DNA architecture. We will define the components and function of this ‘dock’, and the resulting rapid cell death that occurs if it is disrupted. We will explore this cell death pathway thoroughly because we think it may help us to develop new cancer therapies.

Funding Amount $1,145,450.00

Funding Scheme Project Grants

Notes Standard Project Grant