The role of necroptosis in development, the immune system and autoimmune pathology [ 2013 - 2015 ]

Also known as: Necroptosis in programmed cell death and autoimmunity

Research Grant

[Cite as]

Researchers: Prof Andreas Strasser (Principal investigator) ,  Prof John Silke

Brief description Programmed cell death plays critical roles in development and cell-turnover in the adult. Defects in this process can cause cancer or autoimmune diseases. We will use genetic and biochemical approaches to define the individual roles of necroptosis, a newly described cell death process, and those overlapping with apoptosis in normal development and cell-turnover as well as in cancer and autoimmune diseases. The objective of this work is to identify potential targets for therapeutic intervention in cancer or immunopathology.

Funding Amount $AUD 454,105.58

Funding Scheme Project Grants

Notes Standard Project Grant

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