The role of mutant cyclin F in amyotrophic lateral sclerosis [ 2016 - 2018 ]

Research Grant

Researchers: A/Pr Ian Blair (Principal investigator) ,  A/Pr Julie Atkin ,  A/Pr Justin Yerbury ,  Dr Lezanne Ooi ,  Prof Roger Chung

Brief description Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease, MND) is characterised by rapid paralysis leading to death within 2 to 5 years of onset. There are no effective diagnostic tests or treatments. Confusion remains around the primary cause of paralysis. We recently discovered ALS gene mutations that disrupt normal nerve function, a process known as abnormal protostasis. This gives us a unique opportunity to unlock the primary cause of paralysis and develop animal models of ALS

Funding Amount $AUD 1,041,704.04

Funding Scheme Project Grants

Notes Standard Project Grant