Role of the Mitochondrial Membrane in Apoptosis [ 2015 - 2017 ]

Research Grant

Researchers: Prof Marie-Isabel Aguilar (Principal investigator) ,  Dr Erinna Lee

Brief description The Bcl-2 family of proteins is crucial for apoptosis (a form of programmed cell death) regulation. They target the mitochondrial outer membrane where they interact to determine cell fate. We will evaluate the membrane interactions of the Bcl-2 proteins in complementary biophysical and cellular experiments to redefine our understanding of the mechanism of apoptosis and provide new avenues for the development of compounds to selectively modulate diseases in which apoptosis is unregulated.

Funding Amount $AUD 536,668.48

Funding Scheme Project Grants

Notes Standard Project Grant