Research Grant
[Cite as http://purl.org/au-research/grants/nhmrc/1145766]Researchers: Prof Christopher Liddle (Principal investigator) , A/Pr Leon Adams
Brief description When a fatty liver progresses to develop inflammation, patients are at-risk of liver-related morbidity and death. Currently, there are no effective therapies. From human studies, we have discovered that a lipid modifying enzyme (MBOAT7) profoundly regulates liver inflammation. In this proposal, we will obtain a detailed understanding of how the activity of this pathway modulates inflammation. We expect to show that MBOAT7 is a novel ‘druggable’ pathway for the treatment of liver inflammation.
Funding Amount $AUD 860,216.76
Funding Scheme Project Grants
Notes Standard Project Grant
- PURL : http://purl.org/au-research/grants/nhmrc/1145766
- nhmrc : 1145766