grant

The role of MBOAT7 in hepatic inflammation: implications for therapy [ 2018 - 2021 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1145766]

Researchers: Prof Christopher Liddle (Principal investigator) ,  A/Pr Leon Adams

Brief description When a fatty liver progresses to develop inflammation, patients are at-risk of liver-related morbidity and death. Currently, there are no effective therapies. From human studies, we have discovered that a lipid modifying enzyme (MBOAT7) profoundly regulates liver inflammation. In this proposal, we will obtain a detailed understanding of how the activity of this pathway modulates inflammation. We expect to show that MBOAT7 is a novel ‘druggable’ pathway for the treatment of liver inflammation.

Funding Amount $AUD 860,216.76

Funding Scheme Project Grants

Notes Standard Project Grant

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