grant

Role of lysosomal acid lipase in regulating insulin secretion [ 2013 - 2015 ]

Also known as: Role of lysosomes in regulating insulin secretion

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1051658]

Researchers: Prof Trevor Biden (Principal investigator)

Brief description Type 2 diabetes (T2D) affects 7% of Australians and is a major cause of morbidity and mortality. A failure of insulin secretion contributes to T2D, and this is linked to the inability of insulin producing ?-cells to use lipids appropriately (lipotoxicity). Here we will study the role of a cellular body called the lysosome to regulate ?-cell lipid metabolism and insulin secretion. This work will greatly increase the understanding of ?-cell failure in T2D.

Funding Amount $AUD 570,928.77

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857