grant

The role of liver Fructose-1,6-phosphatase (FBPase) in body weight regulation [ 2009 - 2011 ]

Also known as: The role of a liver enzyme in controlling body weight

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/566784]

Researchers: Dr Barbara Fam (Principal investigator) ,  A/Pr Sofianos Andrikopoulos

Brief description We have shown that fructose-1,6-bisphosphatase (FBPase), an enzyme important in producing sugar from the liver and one that is connected to Type 2 diabetes, does not cause an increase in sugar production when there is more of the enzyme in mouse livers. It does, however, lower both body weight and the amount of food the mice consume. We therefore hypothesise that liver FBPase is important in controlling body weight in humans and our project aims to find out exactly how and why this happens.

Funding Amount $AUD 494,718.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857