The role of lipooligosaccharide phosphoethanolamine transferases in the pathogenesis of Neisseria meningitidis and N. gonorrhoeae [ 2011 - 2014 ]

Also known as: Interfering with lipid biosynthesis in bacterial pathogens

Research Grant

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Researchers: A/Pr Charlene Kahler (Principal investigator) ,  Prof Russell Carlson Prof Martin Scanlon Prof Alice Vrielink

Brief description Neisseria meningitidis is the causative agent of meningococcal disease, a rapidly transmissible form of fatal sepsis. The related pathogen, N. gonorrhoeae, causes the sexually transmitted gonorrhoeae and is implicated in the loss of fertility in 10% of patients. This project will analyse the function of a protein necessary for the ability of the both pathogens to cause disease. We will further characterize the function of this protein and determine whether it is a viable candidate for the development of drug therapy.

Funding Amount $AUD 574,890.52

Funding Scheme Project Grants

Notes Standard Project Grant

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